Glossary

AHRQ
The Agency for Healthcare Research and Quality. AHRQ is one of the sponsors of COMPARE-UF.
Anemia
A low blood count or lack of healthy red blood cells. Anemia can result when fibroids cause heavy bleeding.
COMPARE-UF
Comparing Options for Management: Patient Centered Results for Uterine Fibroids.
Consent
The process of agreeing to participate in the registry.
DCRI
Duke Clinical Research Institute. The coordinating center for COMPARE-UF.
Endometrium
The inner lining of the uterus. See also myometrium and perimetrium.
Endometrial ablation
A surgical procedure that destroys the lining of the uterus. This might be used to treat heavy bleeding due to uterine fibroids. Learn more.
Fibroid
A non-cancerous growth in the inside, outside, or muscle of the uterus.
GnRHa
Gonadotropin releasing hormone agonist medication, such as Lupron.
Hysterectomy
Removal of the uterus. May be total (removal of uterus, cervix), partial (removal of the uterus), radial (removal of uterus, cervix, and other structures in the pelvis).
IUD
Intrauterine device. A temporary method of birth control that involves placement of a device inside the uterus.
Menopause
When menstrual periods stop completely. A woman is menopausal when she has not had a spontaneous menstrual period for 12 months.
Menstrual periods
Vaginal bleeding that occurs about once per month in women who ovulate and are not pregnant.
Miscarriage
Pregnancy loss prior to 20 weeks gestation.
MRgFUS
Magnetic resonance-guided focused ultrasound. A noninvasive procedure to destroy fibroids using a high intensity ultrasound beam.
Myolysis
Using ultrasound guided radio frequency to destroy fibroid tissue.
Myomectomy
Surgical removal of fibroids.
Myometrium
The middle layer of the wall of the uterus. See also endometrium and perimetrium.
PCORI
The Patient-Centered Outcomes Research Institute is an independent nonprofit, nongovernmental organization providing the funding for COMPARE-UF.
Pedunculated
Attached by a stalk. Pedunculated fibroids can be on the inside or outside of the uterus.
Perimetrium
The outside layer of the uterus. See also endometrium and myometrium.
Radiofrequency ablation (RFA)
Using high energy radion waves to destroy fibroids.
SERM
Selective estrogen receptor modulators. Hormone-like medications that might reduce the size or limit the growth of fibroids. Examples include tamoxifen, raloxifene, and toremifene.
SPRM
Selective progesterone receptor modulators. Examples include mifepristone (RU-486), ulipristal acetate, asoprisnil, telapristone.
Submucosal
Refers to fibroids just under the lining of the uterus (endometrium).
Subserosal
Refers to fibroids that develop on the outside of the uterus.
Uterine artery embolization (UAE)
A procedure typically performed by an interventional radiologist to block the blood supply to the fibroid.